Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CPN1 | P15169 | 1/20 | 0.37 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.37 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.35 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.35 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.35 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.34 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.34 |
| ▸ | SLC6A11 | P48066 | 2/20 | 0.34 |
| ▸ | SLC6A13 | Q9NSD5 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31511542 | 0.89 | HRH3 (0.44) | HRH3HRH4KMT2ACPN1CPB2 | |
| SCHEMBL606458 | 0.83 | — | — | |
| Hydrochloric Acid SCHEMBL31599906 | 0.82 | HRH3 (0.39) | HRH3HRH4KMT2ACPN1CPB2 | |
| SCHEMBL9111422 | 0.81 | HRH3 (0.40) | HRH3HRH4KMT2ACPN1CPB2 | |
| SCHEMBL5808150 | 0.80 | KMT2A (0.44) | HRH3HRH4KMT2ACPN1CPB2 | |
| SCHEMBL1098260 | 0.77 | — | — | |
| SCHEMBL7704486 | 0.76 | HRH3 (0.53) | HRH3HRH4KMT2ACPN1CPB2 | |
| SCHEMBL4708069 | 0.76 | HRH3 (0.47) | HRH3HRH4KMT2ACPN1CPB2 | |
| SCHEMBL11801552 | 0.75 | — | — | |
| SCHEMBL5806827 | 0.74 | SLC6A1 (0.41) | HRH3HRH4KMT2ACPN1CPB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4573095-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2025-06-25 | — | — | EP | disclosed |
| WO-2024040131-A1 | PYRIDOPYRIMIDINE KRAS INHIBITORS | Treeline Biosciences, Inc. (US) | 2024-02-22 | — | — | WO | disclosed |