Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.41 |
| ▸ | HTR6 | P50406 | 6/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759190 | 1.00 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| SCHEMBL27140921 | 1.00 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| SCHEMBL27109421 | 1.00 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| SCHEMBL27108206 | 1.00 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| Hydrochloric Acid SCHEMBL27145489 | 0.99 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| Hydrochloric Acid SCHEMBL27144639 | 0.99 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| Hydrochloric Acid SCHEMBL27144637 | 0.99 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| Hydrochloric Acid SCHEMBL27145490 | 0.99 | RECQL (0.46) | RECQLNOD1CXCL8HTR6CA12 | |
| SCHEMBL27153056 | 0.89 | LMNA (0.41) | RECQLNOD1HTR6CA12CA2 | |
| SCHEMBL27153054 | 0.89 | LMNA (0.41) | RECQLNOD1HTR6CA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044098-A2 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-29 | — | — | WO | disclosed |