Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 17/20 | 0.41 |
| ▸ | ELOC | Q15369 | 2/20 | 0.35 |
| ▸ | ELOB | Q15370 | 2/20 | 0.35 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.35 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | PRKACA | P17612 | 1/20 | 0.34 |
| ▸ | GSK3A | P49840 | 1/20 | 0.34 |
| ▸ | GSK3B | P49841 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30759988 | 0.92 | VHL (0.48) | VHLELOCELOBROCK1PRKACA | |
| SCHEMBL30760092 | 0.91 | VHL (0.41) | VHLELOCELOB | |
| SCHEMBL30760175 | 0.89 | VHL (0.42) | VHLELOCELOB | |
| SCHEMBL30760047 | 0.88 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL30759995 | 0.88 | VHL (0.41) | VHLELOCELOBROCK2 | |
| SCHEMBL30760079 | 0.87 | VHL (0.43) | VHLELOCELOB | |
| SCHEMBL30759942 | 0.87 | VHL (0.45) | VHLELOCELOB | |
| SCHEMBL27360158 | 0.86 | VHL (0.42) | VHLELOCELOBROCK1ROCK2 | |
| SCHEMBL30760178 | 0.86 | VHL (0.42) | VHLELOCELOBROCK1ROCK2 | |
| SCHEMBL30760093 | 0.85 | VHL (0.40) | VHLELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |