Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 16/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | ELOC | Q15369 | 2/20 | 0.38 |
| ▸ | ELOB | Q15370 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760178 | 1.00 | VHL (0.42) | VHLDPP4ELOCELOBMAPK1 | |
| SCHEMBL27359673 | 0.91 | VHL (0.43) | VHLDPP4ELOCELOBMAPK1 | |
| SCHEMBL30760038 | 0.91 | VHL (0.51) | VHLDPP4ELOCELOBMAPK1 | |
| SCHEMBL27360242 | 0.91 | VHL (0.45) | VHLDPP4ELOCELOBMAPK1 | |
| SCHEMBL30760141 | 0.90 | DPP4 (0.47) | VHLDPP4ELOCELOB | |
| SCHEMBL30760049 | 0.88 | VHL (0.43) | VHLDPP4ELOCELOB | |
| SCHEMBL30759968 | 0.87 | VHL (0.43) | VHLDPP4ELOCELOBROCK2 | |
| SCHEMBL30760065 | 0.86 | VHL (0.41) | VHLELOCELOBROCK2ROCK1 | |
| SCHEMBL30760062 | 0.86 | VHL (0.44) | VHLDPP4ELOCELOB | |
| SCHEMBL30759931 | 0.85 | VHL (0.44) | VHLDPP4ELOCELOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024040080-A1 | KRAS INHIBITOR CONJUGATES | ERASCA, INC. (US) | 2024-02-22 | — | — | WO | disclosed |