Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DNM1 | Q05193 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.33 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 3/20 | 0.31 |
| ▸ | GBA1 | P04062 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL271218 | 0.74 | — | — | |
| SCHEMBL27769660 | 0.74 | — | — | |
| SCHEMBL270624 | 0.74 | — | — | |
| SCHEMBL5178534 | 0.74 | — | — | |
| SCHEMBL303800 | 0.72 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL9660374 | 0.72 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL1061735 | 0.72 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL10703408 | 0.72 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL14679618 | 0.72 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 | |
| SCHEMBL271300 | 0.72 | DNM1 (0.52) | DNM1TSHRTHRBS1PR2S1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |