Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC37A4 | O43826 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | CASP7 | P55210 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | FTO | Q9C0B1 | 2/20 | 0.40 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30760694 | 0.95 | SLC37A4 (0.48) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL30760706 | 0.93 | MEN1 (0.42) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL15427167 | 0.89 | TTR (0.42) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL15427128 | 0.87 | ELANE (0.50) | TTRALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL15427185 | 0.86 | TTR (0.42) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL15427133 | 0.86 | TTR (0.46) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL15427184 | 0.86 | TTR (0.56) | TTRALDH1A1KDM4EMEN1LMNA | |
| SCHEMBL30760692 | 0.84 | TTR (0.56) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL15427084 | 0.83 | TTR (0.43) | SLC37A4TTRALDH1A1KDM4EMEN1 | |
| SCHEMBL30760687 | 0.82 | SLC37A4 (0.50) | SLC37A4TTRALDH1A1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4540224-A1 | COMPOUNDS AND METHOD FOR UPREGULATION OF P53 THROUGH INDUCTION OF MDM2 DEGRADATION | Georgia State University Research Foundation, Inc. (US) | 2025-04-23 | — | — | EP | disclosed |
| WO-2023250318-A1 | COMPOUNDS AND METHOD FOR UPREGULATION OF P53 THROUGH INDUCTION OF MDM2 DEGRADATION | GEORGIA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-12-28 | — | — | WO | disclosed |