SCHEMBL30760973

SCHEMBL30760973

C#CC(O)c1ccc2ccccc2c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.57
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
ATM Q13315 1/20 0.49
SLC6A2 P23975 10/20 0.45
SLC6A4 P31645 10/20 0.45
SLC6A3 Q01959 10/20 0.45
KCNH2 Q12809 5/20 0.45
CYP2D6 P10635 2/20 0.45
AOC3 Q16853 1/20 0.45
CYP1A2 P05177 1/20 0.45
TSHR P16473 1/20 0.45
HIF1A Q16665 1/20 0.45
CYP3A4 P08684 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11357180 1.00 UGT2B7 (0.57) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL9547920 0.83 UGT2B7 (0.61) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL27536762 0.80 TSHR (0.57) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL7434128 0.80 UGT2B7 (0.57) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL3041531 0.80 TSHR (0.57) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL434216 0.76 UGT2B7 (0.68) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL30033673 0.76 UGT2B7 (0.68) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL600527 0.76 UGT2B7 (0.68) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL29184903 0.75 ESR1 (0.46) TSHR
SCHEMBL28685361 0.74 UGT2B7 (0.46) UGT2B7MEN1KMT2AATMSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117486673-A Method for synthesizing naphthalene group-containing propargyl fluoride compound by using sulfur hexafluoride 国网安徽省电力有限公司电力科学研究院 2024-02-02 CN disclosed