SCHEMBL434216

SCHEMBL434216

OC(O)c1ccc2ccccc2c1

nearest known ligand 0.68

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
UGT2B7 P16662 1/20 0.68
MEN1 O00255 2/20 0.57
KMT2A Q03164 2/20 0.57
ATM Q13315 1/20 0.57
SLC6A2 P23975 10/20 0.52
SLC6A4 P31645 10/20 0.52
SLC6A3 Q01959 10/20 0.52
KCNH2 Q12809 5/20 0.52
CYP2D6 P10635 2/20 0.52
CYP1A2 P05177 2/20 0.52
AOC3 Q16853 1/20 0.52
TSHR P16473 1/20 0.52
HIF1A Q16665 1/20 0.52
CYP3A4 P08684 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11064343 0.93 UGT2B7 (0.59) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL13558378 0.89 UGT2B7 (0.52) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL30033673 0.85 UGT2B7 (0.68) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL600527 0.85 UGT2B7 (0.68) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL3169520 0.84 UGT2B7 (0.48) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL445001 0.81 UGT2B7 (1.00) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL8474125 0.81 UGT2B7 (0.63) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL15352903 0.81 UGT2B7 (0.63) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL110360 0.81 UGT2B7 (1.00) UGT2B7MEN1KMT2AATMSLC6A2
SCHEMBL7649891 0.81 UGT2B7 (0.63) UGT2B7MEN1KMT2AATMSLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8754221-B2 Optically active cyclic alcohol compound and method for preparing the same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2014-06-17 US claimed
US-20130237708-A1 Optically Active Cyclic Alcohol Compound And Method For Preparing The Same MITSUBISHI TANABE PHARMA CORPORATION (JP) 2013-09-12 US claimed
EP-1944291-B1 Optically active cyclic alcohol compound and method for producing same MITSUBISHI TANABE PHARMA CORP (JP) 2012-06-13 EP claimed
US-20100152451-A1 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME MITSUBISHI TANABE PHARMA CORPORATION (JP) 2010-06-17 US claimed
EP-1944291-A1 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PRODUCING SAME Mitsubishi Tanabe Pharma Corporation (JP) 2008-07-16 EP claimed
CN-1361759-A 6-hydroxy-2-naphthyl carbinol and process for producing the same MITSUBISHI CHEM CORP (JP) 2002-07-31 CN claimed
US-5527899-A STABILIZATION THE SINGLE-STRAND OLIGONUCLEOTIDE TO EXONUCLEASE DEGRADATION GILEAD SCIENCES, INC. (US) 1996-06-18 US claimed
US-5399676-A DNA sequence identification GILEAD SCIENCES (US) 1995-03-21 US claimed
EP-0180188-B1 A COMPOSITION FOR INCREASING THE ANTI-CANCER ACTIVITY OF AN ANTI-CANCER COMPOUND OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1992-04-15 EP claimed
US-20230331689-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME LT MATERIALS CO., LTD. (KR) 2023-10-19 US disclosed
US-20210317490-A1 ANTICANCER COMPOUNDS PHARMA MAR, S.A., (ES) 2021-10-14 US disclosed
US-20210139521-A1 DIARYL TREHALOSE COMPOUNDS AND USES THEREOF THE UNIV OF MONTANA (US) 2021-05-13 US disclosed
CN-108884212-B Maleimide resin, curable resin composition and cured product thereof 日本化药株式会社 2020-12-29 CN disclosed
EP-3640236-A1 A METHOD OF PRODUCING INGENOL-3-ANGELATE LEO LABORATORIES LIMITED (IE) 2020-04-22 EP disclosed
EP-0311387-A2 Aromatic amine resins, their production process and thermosetting resin compositions making use of the same MITSUI TOATSU CHEMICALS, Inc. (JP) 1989-04-12 EP disclosed
US-4518609-A ANTITUMOR, SKIN DISORDERS SRI INTERNATIONAL (US) 1985-05-21 US disclosed
US-4456618-A ANTITUMOR AGENTS, TREATMENT OF SKIN DISORDERS SRI INTERNATIONAL (US) 1984-06-26 US disclosed
US-4436804-A Light-sensitive polymeric diazonium condensates and reproduction compositions and materials therewith AMERICAN HOECHST CORPORATION (US) 1984-03-13 US disclosed
US-4101274-A DISPERSE DYES, POLYESTERS HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-18 US disclosed
US-4025553-A Production of o-hydroxybenzyl alcohols SHIONOGI & CO., LTD. (JA) 1977-05-24 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210317490-A1 ANTICANCER COMPOUNDS SLC75A1, SLC15A1, LCT UGT2B7 1401/4885MEN1 1707/4885KMT2A 944/4885
US-20100152451-A1 OPTICALLY ACTIVE CYCLIC ALCOHOL COMPOUND AND METHOD FOR PREPARING THE SAME ADH1C, ADH1A, ADH5 UGT2B7 216/4885MEN1 2662/4885KMT2A 1394/4885
US-20130237708-A1 Optically Active Cyclic Alcohol Compound And Method For Preparing The Same ADH1C, ADH1A, ADH5 UGT2B7 216/4885MEN1 2662/4885KMT2A 1394/4885
US-20230331689-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT COMPRISING SAME CRY1, CRY2, CYP1A1 UGT2B7 184/4885MEN1 225/4885KMT2A 574/4885
US-20210139521-A1 DIARYL TREHALOSE COMPOUNDS AND USES THEREOF TREH, STT3B, DDOST UGT2B7 1975/4885MEN1 3708/4885KMT2A 4228/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.