Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.52 |
| ▸ | HPGDS | O60760 | 2/20 | 0.50 |
| ▸ | IDO1 | P14902 | 2/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.46 |
| ▸ | SCN4A | P35499 | 2/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.42 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.42 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18622292 | 0.78 | SCN4A (0.54) | NOTUMHPGDSIDO1BCAT2HCAR2 | |
| Hydrochloric Acid SCHEMBL15327060 | 0.75 | CYP4F2 (0.60) | NOTUMIDO1SCN4ACYP4F2CYP4A11 | |
| SCHEMBL3362110 | 0.74 | PDPK1 (0.50) | NOTUMHPGDSIDO1BCAT2HCAR2 | |
| SCHEMBL17791787 | 0.72 | HCAR2 (0.61) | NOTUMHPGDSIDO1HCAR2SCN4A | |
| SCHEMBL3068150 | 0.71 | SCN4A (0.62) | NOTUMHPGDSIDO1HCAR2SCN4A | |
| SCHEMBL104517 | 0.70 | SCN4A (0.79) | NOTUMHPGDSIDO1SCN4APDPK1 | |
| SCHEMBL29585516 | 0.68 | HPGDS (0.53) | NOTUMHPGDSIDO1LTA4HPIM1 | |
| SCHEMBL22638870 | 0.68 | IDO1 (0.71) | NOTUMHPGDSIDO1SCN4AADRA1A | |
| SCHEMBL31662977 | 0.68 | NOTUM (0.49) | NOTUMHPGDSIDO1SCN4APDPK1 | |
| SCHEMBL16433080 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500795-A | Receptor interacting protein 1 inhibitor, preparation and application thereof | 维泰瑞隆有限公司 | 2024-02-02 | — | — | CN | disclosed |