SCHEMBL3076205

SCHEMBL3076205

C1CCC/N=N\CC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3076207 1.00
SCHEMBL3134402 1.00 NOS3 (0.30)
SCHEMBL1801495 1.00 NOS3 (0.30)
SCHEMBL11295644 1.00 NOS3 (0.30)
SCHEMBL11294671 1.00 NOS3 (0.30)
SCHEMBL1801493 1.00 NOS3 (0.30)
SCHEMBL1585213 1.00
SCHEMBL1801693 1.00
SCHEMBL3134406 1.00 NOS3 (0.30)
SCHEMBL17663543 1.00 NOS3 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240124904-A1 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES AGAIN BIO APS (DK) 2024-04-18 US claimed
EP-3744830-B1 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES GENOMATICA INC (US) 2023-11-22 EP claimed
EP-3021847-B1 SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH HELMHOLTZ ZENTRUM MUENCHEN DEUTSCHES FORSCHUNGSZENTRUM GESUNDHEIT & UMWELT GMBH (DE) 2023-06-07 EP claimed
US-RE48992-E1 Spiroquinoxaline derivatives as inhibitors of non-apoptotic regulated cell-death HELMHOLTZ ZENTRUM MÜNCHEN-DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2022-03-29 US claimed
EP-3744830-A1 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES Genomatica, Inc. (US) 2020-12-02 EP claimed
US-10647687-B2 Spiropyrazine derivatives as inhibitors of non-apoptotic regulated cell-death HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2020-05-12 US claimed
US-10597684-B2 Methods and organisms with increased carbon flux efficiencies GENOMATICA, INC. (US) 2020-03-24 US claimed
US-10280179-B2 Spiroquinoxaline derivatives as inhibitors of non-apoptotic regulated cell-death HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2019-05-07 US claimed
US-20180362475-A1 SPIROPYRAZINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH HELMHOLTZ ZENTRUM MÜNCHEN DEUTSCHES FORSCHUNGSZENTRUM FÜR GESUNDHEIT UND UMWELT (GMBH) (DE) 2018-12-20 US claimed
US-20180065982-A1 SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH HELMHOLTZ ZENTRUM MUNCHEN DEUTSCHES FORSCHUNGSZENTRUM FUR GESUNDHEIT UND UMWELT (GMBH) (DE) 2018-03-08 US claimed
EP-3217982-A1 SPIROPYRAZINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH Helmholtz Zentrum München Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2017-09-20 EP claimed
US-20160326553-A1 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES GENOMATICA, INC. (US) 2016-11-10 US claimed
EP-3087174-A2 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES Genomatica, Inc. (US) 2016-11-02 EP claimed
US-20160222025-A1 SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH HELMHOLTZ ZENTRUM MUNCHEN (DE) 2016-08-04 US claimed
EP-3021847-A1 SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2016-05-25 EP claimed
WO-2016075137-A1 SPIROPYRAZINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2016-05-19 WO claimed
WO-2015100338-A2 METHODS AND ORGANISMS WITH INCREASED CARBON FLUX EFFICIENCIES GENOMATICA, INC. (US) 2015-07-02 WO claimed
WO-2015007730-A1 SPIROQUINOXALINE DERIVATIVES AS INHIBITORS OF NON-APOPTOTIC REGULATED CELL-DEATH Helmholtz Zentrum München - Deutsches Forschungszentrum für Gesundheit und Umwelt (GmbH) (DE) 2015-01-22 WO claimed
US-20130303723-A1 MICROORGANISMS AND METHODS FOR THE BIOSYNTHESIS OF ADIPATE, HEXAMETHYLENEDIAMINE AND 6-AMINOCAPROIC ACID AGAIN BIO APS (DK) 2013-11-14 US claimed
US-4317772-A Process for preparation of aminated sulfurized olefins using alkaline earth metal compounds STANDARD OIL COMPANY (INDIANA) (US) 1982-03-02 US claimed