Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 14/20 | 0.44 |
| ▸ | ATR | Q13535 | 3/20 | 0.43 |
| ▸ | SOS1 | Q07889 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 8/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.42 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.42 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.42 |
| ▸ | ATRIP | Q8WXE1 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762544 | 0.82 | PIK3CA (0.49) | HTTATML3MBTL1PIK3CBATR | |
| SCHEMBL30762375 | 0.79 | HTT (0.49) | HTTATML3MBTL1PIK3CBATR | |
| SCHEMBL30762530 | 0.79 | HTT (0.49) | HTTATML3MBTL1ATRSOS1 | |
| SCHEMBL30762555 | 0.79 | PIK3CA (0.57) | HTTATML3MBTL1PIK3CBPIK3CA | |
| SCHEMBL30762384 | 0.79 | PIK3CA (0.57) | HTTATML3MBTL1PIK3CBPIK3CA | |
| SCHEMBL30762648 | 0.79 | PIK3CA (0.57) | HTTATML3MBTL1PIK3CBPIK3CA | |
| SCHEMBL30762559 | 0.78 | PIK3CB (0.48) | HTTATML3MBTL1PIK3CBPIK3CA | |
| SCHEMBL30762403 | 0.75 | PIK3CB (0.46) | HTTATML3MBTL1PIK3CBATR | |
| SCHEMBL30762411 | 0.72 | HTT (0.54) | HTTATML3MBTL1PIK3CBATR | |
| SCHEMBL910071 | 0.70 | PIK3CB (0.81) | PIK3CBPIK3CAPIK3CDPIK3CGPIK3R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |