Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.54 |
| ▸ | ATM | Q13315 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | ATR | Q13535 | 4/20 | 0.48 |
| ▸ | ATRIP | Q8WXE1 | 3/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30762583 | 0.88 | CNR1 (0.40) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762663 | 0.85 | HTT (0.54) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762530 | 0.81 | HTT (0.49) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762537 | 0.81 | HTT (0.49) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762375 | 0.81 | HTT (0.49) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL23110061 | 0.80 | HTT (0.70) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762523 | 0.76 | ALDH1A1 (0.49) | HTTL3MBTL1MAPK1KMT2AMEN1 | |
| SCHEMBL30762689 | 0.74 | PTGES (0.36) | — | |
| SCHEMBL30762373 | 0.73 | KDM4E (0.46) | HTTATML3MBTL1ATRATRIP | |
| SCHEMBL30762620 | 0.72 | KDM4E (0.45) | HTTATML3MBTL1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024026423-A1 | SUBSTITUTED QUINOLINE DERIVATIVES AS PI3K INHIBITORS | BLACK DIAMOND THERAPEUTICS, INC. (US) | 2024-02-01 | — | — | WO | disclosed |