Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | CA12 | O43570 | 2/20 | 0.58 |
| ▸ | PPARG | P37231 | 3/20 | 0.51 |
| ▸ | PPARD | Q03181 | 3/20 | 0.51 |
| ▸ | PPARA | Q07869 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | HPGD | P15428 | 5/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20839393 | 1.00 | CA9 (0.58) | CA9CA12PPARGPPARDPPARA | |
| SCHEMBL22431636 | 0.88 | ALDH1A1 (0.50) | CA9PPARGPPARDPPARAALDH1A1 | |
| SCHEMBL20839412 | 0.86 | CA12 (0.53) | CA9CA12PPARGPPARDPPARA | |
| SCHEMBL30762859 | 0.86 | CA12 (0.53) | CA9CA12PPARGPPARDPPARA | |
| SCHEMBL20839069 | 0.86 | CA9 (0.52) | CA9CA12PPARGPPARDPPARA | |
| SCHEMBL30762923 | 0.86 | CA9 (0.52) | CA9CA12PPARGPPARDPPARA | |
| SCHEMBL30057343 | 0.84 | CA9 (0.50) | CA9CA12PPARGPPARDPPARA | |
| SCHEMBL20839066 | 0.81 | ALDH1A1 (0.75) | CA9CA12ALDH1A1HPGDUSP2 | |
| SCHEMBL20839468 | 0.81 | ALDH1A1 (0.75) | CA9CA12ALDH1A1HPGDUSP2 | |
| SCHEMBL30763026 | 0.81 | ALDH1A1 (0.75) | CA9CA12ALDH1A1HPGDUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | claimed |
| CN-111386261-B | Coumarin derivatives, process for their preparation and their use in the treatment of cancer | 利德发现中心有限责任公司 | 2024-03-22 | — | — | CN | disclosed |