SCHEMBL3076292

SCHEMBL3076292

CN1CCCCC1(C)C(NC(=O)c1cccc(C(F)(F)F)c1Cl)c1ccccc1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 18/20 0.65
CTSS P25774 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL3083599 0.99 SLC6A9 (0.64) SLC6A9CTSS
SCHEMBL5146391 0.89 SLC6A9 (0.65) SLC6A9CTSS
SCHEMBL8085384 0.84 SLC6A9 (0.69) SLC6A9
SCHEMBL13970066 0.84 SLC6A9 (0.69) SLC6A9
SCHEMBL13970173 0.84 SLC6A9 (0.69) SLC6A9
SCHEMBL3244222 0.83 SLC6A9 (0.65) SLC6A9CTSS
SCHEMBL17684029 0.82 SLC6A9 (0.62) SLC6A9CTSS
SCHEMBL3231206 0.81 SLC6A9 (0.62) SLC6A9CTSS
SCHEMBL3239482 0.81 SLC6A9 (0.62) SLC6A9CTSS
SCHEMBL3237575 0.81 SLC6A9 (0.61) SLC6A9CTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1882541-B N- [ phenyl (alkyl-2-piperidinyl) methyl ] benzamide derivatives, their preparation and their therapeutic use SANOFI AVENTIS 2011-07-06 CN claimed
US-7790753-B2 Derivatives of N-[phenyl(alkylpiperidine-2-yl)methyl]benzamide, preparation method thereof and application of same in therapeutics SANOFI-AVENTIS (FR) 2010-09-07 US claimed
EP-1682503-B1 DERIVATIVES OF N-[PHENYL(ALKYLPIPERIDINE-2-YL)METHYL]BENZAMIDE, PREPARATION METHOD THEREOF AND APPLICATION OF SAME IN THERAPEUTICS SANOFI AVENTIS (FR) 2007-04-11 EP disclosed