SCHEMBL30763286

CC[C@H](C)[C@H](NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@@H](N)CO)C(C)C)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](Cc1c[nH]cn1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)O

nearest known ligand 0.52

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PTH1R	Q03431	8/20	0.52

▸	CALCR	P30988	3/20	0.50

▸	CRHR1	P34998	1/20	0.50

▸	CRHR2	Q13324	1/20	0.50

▸	KEAP1	Q14145	1/20	0.47

▸	GLP1R	P43220	2/20	0.47

▸	BACE1	P56817	1/20	0.47

▸	F2	P00734	1/20	0.46

▸	RXFP1	Q9HBX9	1/20	0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL30136427	0.94	PTH1R (0.55)	PTH1RCALCRCRHR1CRHR2GLP1R
SCHEMBL29407403	0.91	PTH1R (0.59)	PTH1RCALCRCRHR1CRHR2GLP1R
SCHEMBL31303964	0.91	PTH1R (0.59)	PTH1RCALCRCRHR1CRHR2GLP1R
SCHEMBL30136490	0.91	PTH1R (0.59)	PTH1RCALCRCRHR1CRHR2GLP1R
SCHEMBL31307253	0.89	CRHR1 (0.49)	PTH1RCALCRCRHR1CRHR2KEAP1
SCHEMBL29805149	0.89	CALCR (0.48)	CALCRCRHR1CRHR2KEAP1GLP1R
SCHEMBL30449532	0.88	PTH1R (0.65)	PTH1RCALCRGLP1RRXFP1
SCHEMBL30262081	0.86	CALCR (0.59)	CALCRCRHR1CRHR2KEAP1GLP1R
SCHEMBL30436811	0.85	GLP1R (0.56)	CALCRCRHR1CRHR2GLP1RF2
SCHEMBL31656529	0.84	CALCR (0.62)	CALCRCRHR1CRHR2GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-117586372-A	Long-acting teriparatide compound	成都奥达生物科技有限公司	2024-02-23	—	—	CN	claimed
CN-117586372-A	Long-acting teriparatide compound	成都奥达生物科技有限公司	2024-02-23	—	—	CN	disclosed