Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | BCL6 | P41182 | 1/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.34 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.34 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.34 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21614658 | 1.00 | CYP2C19 (0.51) | CYP2C19CYP2C9KCNH2ADORA2AADORA1 | |
| SCHEMBL21614652 | 0.84 | CYP2C19 (0.41) | CYP2C19CYP2C9KCNH2ADORA2AADORA1 | |
| SCHEMBL21611978 | 0.80 | CYP2C19 (0.44) | CYP2C19CYP2C9KCNH2ADORA2AADORA1 | |
| SCHEMBL21614731 | 0.77 | CYP2C19 (0.81) | CYP2C19CYP2C9KCNH2LMNACDK2 | |
| SCHEMBL21611951 | 0.69 | CYP2C19 (0.81) | CYP2C19CYP2C9KCNH2LMNACDK2 | |
| SCHEMBL21612041 | 0.69 | CYP2C19 (0.79) | CYP2C19CYP2C9KCNH2 | |
| SCHEMBL21611977 | 0.67 | CYP2C19 (0.39) | CYP2C19CYP2C9KCNH2ADORA2AADORA1 | |
| SCHEMBL21614703 | 0.66 | CYP2C19 (0.68) | CYP2C19CYP2C9KCNH2LMNACDK2 | |
| SCHEMBL21614737 | 0.66 | CYP2C19 (0.73) | CYP2C19CYP2C9KCNH2 | |
| SCHEMBL17027854 | 0.60 | PIK3CD (0.51) | KCNH2ADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11883387-B2 | PqsR inverse agonists | Helmholtz-Zentrum für Infektionsforschung GmbH (DE) | 2024-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11883387-B2 | PqsR inverse agonists | QRFPR, P2RY11, QARS1 | CYP2C19 1824/4885CYP2C9 2997/4885KCNH2 2343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.