Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30763605 | 1.00 | KMT2A (0.41) | KMT2AMEN1MMP13GPR119NR1H2 | |
| SCHEMBL30763586 | 1.00 | KMT2A (0.41) | KMT2AMEN1MMP13GPR119NR1H2 | |
| SCHEMBL16415382 | 0.92 | KMT2A (0.44) | KMT2AMEN1MMP13GPR119P2RX7 | |
| SCHEMBL25235454 | 0.86 | CYP2D6 (0.44) | KMT2AMEN1MMP13GPR119 | |
| SCHEMBL30763602 | 0.86 | STAT3 (0.40) | KMT2A | |
| SCHEMBL16414765 | 0.85 | GPR119 (0.47) | KMT2AMEN1MMP13GPR119PRMT5 | |
| SCHEMBL16414766 | 0.85 | GPR119 (0.47) | KMT2AMEN1MMP13GPR119PRMT5 | |
| SCHEMBL27097843 | 0.85 | KMT2A (0.43) | KMT2AMEN1MMP13GPR119P2RX7 | |
| SCHEMBL27097866 | 0.84 | GPR119 (0.42) | KMT2AMEN1MMP13GPR119PRMT5 | |
| SCHEMBL15600231 | 0.83 | GPR119 (0.53) | KMT2AMEN1MMP13GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568946-A1 | MACROCYCLIC BCL6 DEGRADERS | Dana-Farber Cancer Institute, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119585240-A | Macrocyclic BCL6 degrading agents | 丹娜-法伯癌症研究院 | 2025-03-07 | — | — | CN | disclosed |
| WO-2024035688-A1 | MACROCYCLIC BCL6 DEGRADERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2024-02-15 | — | — | WO | disclosed |