SCHEMBL3076504

SCHEMBL3076504

O=C(NC1CCCCC1)C(=O)NC1CCCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 1.00
SMN1; SMN2 Q16637 5/20 1.00
RAB9A P51151 4/20 1.00
MAPT P10636 3/20 1.00
EPHX1 P07099 7/20 0.70
ALDH1A1 P00352 2/20 0.70
CYP3A4 P08684 2/20 0.70
KDM4E B2RXH2 1/20 0.70
EPHX2 P34913 1/20 0.70
MAPK1 P28482 1/20 0.70
DUSP3 P51452 1/20 0.70
PTPN5 P54829 1/20 0.70
PTPN11 Q06124 1/20 0.70
HTT P42858 1/20 0.65
POLB P06746 2/20 0.57
MMP2 P08253 3/20 0.56
CA12 O43570 2/20 0.56
CA1 P00915 2/20 0.56
CA2 P00918 2/20 0.56
CA9 Q16790 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8165938 1.00 NPC1 (1.00) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL23736058 1.00 NPC1 (1.00) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL2377367 1.00 NPC1 (1.00) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL6850969 0.97 SMN1; SMN2 (0.94) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL9866491 0.88 SMN1; SMN2 (0.77) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL9065286 0.88 SMN1; SMN2 (0.77) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL8937797 0.87 NPC1 (0.76) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL11407159 0.87 NPC1 (0.76) NPC1SMN1; SMN2RAB9AMAPTEPHX1
SCHEMBL11410738 0.87 NPC1 (0.76) NPC1SMN1; SMN2RAB9AMAPTEPHX1
Hydrochloric Acid SCHEMBL28051161 0.86 SMN1; SMN2 (0.74) NPC1SMN1; SMN2RAB9AMAPTEPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230211599-A1 Lithographic Photopolymer Printing Plate Precursor with Improved Daylight Stability AGFA OFFSET BV (BE) 2023-07-06 US disclosed
US-20230211599-A1 Lithographic Photopolymer Printing Plate Precursor with Improved Daylight Stability AGFA OFFSET BV (BE) 2023-07-06 US disclosed
WO-2021249754-A1 LITHOGRAPHIC PHOTOPOLYMER PRINTING PLATE PRECURSOR WITH IMPROVED DAYLIGHT STABILITY AGFA OFFSET BV (BE) 2021-12-16 WO disclosed
EP-3212705-B1 OXALIC ACID DIAMIDES AS MODIFIERS FOR POLYOLEFIN CATALYSTS FORMOSA PLASTICS CORP USA (US) 2021-03-10 EP disclosed
US-10822438-B2 Catalyst system for enhanced stereo-specificity of olefin polymerization and method for producing olefin polymer FORMOSA PLASTICS CORPORATION (US) 2020-11-03 US disclosed
US-9777084-B2 Catalyst system for olefin polymerization and method for producing olefin polymer FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-03 US disclosed
US-9777084-B2 Catalyst system for olefin polymerization and method for producing olefin polymer FORMOSA PLASTICS CORPORATION, USA (US) 2017-10-03 US disclosed
US-20170240667-A1 Catalyst System for Olefin Polymerization and Method for Producing Olefin Polymer FORMOSA PLASTICS CORPORATION, USA 2017-08-24 US disclosed
US-20170240667-A1 Catalyst System for Olefin Polymerization and Method for Producing Olefin Polymer FORMOSA PLASTICS CORPORATION, USA 2017-08-24 US disclosed
US-9593184-B2 Oxalic acid diamides as modifiers for polyolefin catalysts FORMOSA PLASTICS CORPORATION, USA (US) 2017-03-14 US disclosed
US-20040011252-A1 Non-toxic corrosion-protection pigments based on manganese UNIVERSITY OF DAYTON 2004-01-22 US disclosed
US-20030234063-A1 Non-toxic corrosion-protection conversion coats based on cobalt DAYTON, UNIVERSITY OF 2003-12-25 US disclosed
US-20030230363-A1 Non-toxic corrosion-protection rinses and seals based on cobalt UNIVERSITY OF DAYTON 2003-12-18 US disclosed
US-20030148188-A1 Active materials in the positive electrodes of batteries. Novel methods for preparing the tetraketopiperazine unit-containing compounds include: (i) reacting an oxalyl halide and an oxamide, and adding water or an aqueous alkali IM&T RESEARCH, INC. 2003-08-07 US disclosed
WO-2003060192-A1 NON-TOXIC CORROSION-PROTECTION RINSES AND SEALS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060191-A2 NON-TOXIC CORROSION-PROTECTION CONVERSION COATINGES ABSED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
WO-2003060019-A1 NON-TOXIC CORROSION PROTECTION PIGMENTS BASED ON COBALT UNIVERSITY OF DAYTON (US) 2003-07-24 WO disclosed
EP-0309619-B1 RADIATION SENSITIVE ACRYLATE COMPOSITION Polychrome Corporation (US) 1993-01-27 EP disclosed
EP-0309619-A1 Radiation sensitive acrylate composition Polychrome Corporation (US) 1989-04-05 EP disclosed
US-4782005-A N,N'-diorgano dicarboxamides as oxygen inhibitors in radiation sensitive acrylate compositions POLYCHROME CORP. (US) 1988-11-01 US disclosed