Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.33 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723857 | 1.00 | NR4A2 (0.33) | NR4A2SOS2CASP6PSMB8PSMB5 | |
| SCHEMBL2211013 | 0.79 | ALDH1A1 (0.35) | NR4A2SOS2CASP6PSMB8PSMB5 | |
| SCHEMBL722765 | 0.76 | NR4A2 (0.34) | NR4A2SOS2CASP6PSMB8PSMB5 | |
| SCHEMBL29767254 | 0.76 | NR4A2 (0.34) | NR4A2SOS2CASP6PSMB8PSMB5 | |
| SCHEMBL18340397 | 0.75 | NR4A2 (0.32) | NR4A2SOS2CASP6 | |
| SCHEMBL1849392 | 0.71 | RECQL (0.38) | NR4A2SOS2CASP6 | |
| SCHEMBL2207433 | 0.71 | PSMB8 (0.42) | NR4A2SOS2CASP6PSMB8PSMB5 | |
| SCHEMBL18348153 | 0.71 | NR4A2 (0.35) | NR4A2SOS2CASP6 | |
| SCHEMBL4758600 | 0.71 | NR4A2 (0.32) | NR4A2SOS2CASP6 | |
| SCHEMBL723046 | 0.71 | CSNK2A2 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |