Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | USP28 | Q96RU2 | 1/20 | 0.44 |
| ▸ | USP25 | Q9UHP3 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | CCR5 | P51681 | 2/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | RHEB | Q15382 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23112086 | 1.00 | KDM1A (0.46) | KDM1AGAAMAPTHPGDUSP28 | |
| SCHEMBL1017228 | 0.86 | KDM1A (0.54) | KDM1AGAAMAPTHPGDMAOB | |
| SCHEMBL24057021 | 0.82 | HPGD (0.49) | KDM1AGAAMAPTHPGDMAOB | |
| SCHEMBL15729561 | 0.81 | MAPT (0.57) | KDM1AGAAMAPTHPGDMAOB | |
| SCHEMBL5823983 | 0.80 | USP28 (0.48) | KDM1AGAAMAPTHPGDUSP28 | |
| SCHEMBL23111969 | 0.80 | MEN1 (0.54) | HPGDPTGER1LMNA | |
| SCHEMBL21602390 | 0.80 | GAA (0.50) | GAAMAPTUSP28USP25HTT | |
| SCHEMBL31056430 | 0.79 | GAA (0.43) | GAAMAPTHPGDUSP28USP25 | |
| SCHEMBL25366114 | 0.79 | KDM1A (0.47) | KDM1AHPGDMAOBTHRATHRB | |
| SCHEMBL26927452 | 0.79 | KDM1A (0.51) | KDM1AGAAMAPTHPGDMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112424181-B | Substituted condensed thiophenes as STING modulators | 希泰克斯特私人有限公司 | 2024-02-27 | — | — | CN | disclosed |