Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.36 |
| ▸ | HPGD | P15428 | 4/20 | 0.36 |
| ▸ | ABL1 | P00519 | 3/20 | 0.36 |
| ▸ | BCR | P11274 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | FYN | P06241 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | LIPC | P11150 | 1/20 | 0.34 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765312 | 0.91 | HPGD (0.41) | CCNT1CDK9CYP3A4HPGDABL1 | |
| SCHEMBL27261503 | 0.90 | CCNT1 (0.46) | CCNT1CDK9CYP3A4HPGDTSHR | |
| SCHEMBL30765359 | 0.85 | HSD17B10 (0.44) | CCNT1CDK9HPGDALDH1A1HSD17B10 | |
| SCHEMBL30765169 | 0.84 | CCNT1 (0.37) | CCNT1CDK9HPGDHSD17B10FYN | |
| SCHEMBL27261385 | 0.83 | HPGD (0.37) | CCNT1CDK9CYP3A4HPGDABL1 | |
| SCHEMBL27261616 | 0.82 | CDK9 (0.31) | CDK9 | |
| SCHEMBL30765346 | 0.82 | PDE4B (0.36) | CCNT1CDK9PIK3CD | |
| SCHEMBL30765217 | 0.81 | MAP3K7 (0.34) | CCNT1CDK9FYNLRRK2 | |
| SCHEMBL30765305 | 0.81 | ALOX5AP (0.41) | CCNT1CDK9CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL30765241 | 0.81 | ALOX5AP (0.41) | CCNT1CDK9CYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |