Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765147 | 0.86 | NPC1 (0.51) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL31565117 | 0.81 | PHGDH (0.51) | NPC1HPGDKMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL27267083 | 0.80 | NPC1 (0.42) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL32672625 | 0.80 | NPC1 (0.42) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL27262760 | 0.80 | NPC1 (0.42) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL32672657 | 0.80 | NPC1 (0.42) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL32672563 | 0.80 | NPC1 (0.42) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL32672579 | 0.77 | HSD17B10 (0.39) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL32672542 | 0.77 | HSD17B10 (0.39) | NPC1ALDH1A1HPGDHSD17B10NPSR1 | |
| SCHEMBL32672644 | 0.77 | HSD17B10 (0.39) | NPC1ALDH1A1HPGDHSD17B10NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568970-A1 | FURO PYRIMIDINE DERIVATES | Merck Patent GmbH (DE) | 2025-06-18 | — | — | EP | disclosed |
| CN-119948032-A | Furanopyrimidine derivatives | 默克专利股份有限公司 | 2025-05-06 | — | — | CN | disclosed |
| WO-2024033281-A1 | FURO PYRIMIDINE DERIVATES | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |
| WO-2024033280-A1 | FUROPYRIDIN AND FUROPYRIMIDIN, INHIBITORS OF PI4K, FOR USE IN THE TREATMENT OF PARASITE INFECTION AND MALARIA | MERCK PATENT GMBH (DE) | 2024-02-15 | — | — | WO | disclosed |