SCHEMBL30765462

SCHEMBL30765462

C[C@@H](Nc1ncc(C2=CCOCC2)n(CC(=O)NCc2cc3cnccc3[nH]2)c1=O)c1ccc2oc3ccccc3c2c1

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAPK1 P28482 2/20 0.35
SOS1 Q07889 3/20 0.35
F2 P00734 6/20 0.33
F7 P08709 2/20 0.33
HDAC6 Q9UBN7 1/20 0.31
PRSS1 P07477 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765440 0.88 F7 (0.39) MAPK1F2F7HDAC6PRSS1
SCHEMBL30765753 0.86 F2 (0.34) MAPK1F2F7PRSS1
SCHEMBL30765728 0.85 MAPK1 (0.38) MAPK1SOS1F2PRSS1
SCHEMBL30765730 0.83 SOS1 (0.41) SOS1HDAC6
SCHEMBL30765686 0.82 F2 (0.35) MAPK1F2
SCHEMBL30765642 0.80 MAPK1 (0.35) MAPK1F2HDAC6
SCHEMBL30765882 0.79 SOS1 (0.37) SOS1
SCHEMBL30765603 0.79 F2 (0.35) MAPK1F2HDAC6PRSS1
SCHEMBL30765871 0.79 F2 (0.36) MAPK1F2HDAC6
SCHEMBL30765625 0.79 F2 (0.36) MAPK1F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 EP disclosed
CN-119768164-A Pharmaceutical compounds for treating complement-mediated disorders 阿雷克森制药公司 2025-04-04 CN disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 WO disclosed