Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 6/20 | 0.41 |
| ▸ | EGFR | P00533 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.32 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.32 |
| ▸ | AURKA | O14965 | 1/20 | 0.31 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.31 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | TAF1 | P21675 | 1/20 | 0.31 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765882 | 0.88 | SOS1 (0.37) | SOS1EGFRLMNA | |
| SCHEMBL30765462 | 0.83 | MAPK1 (0.35) | SOS1HDAC6 | |
| SCHEMBL31558425 | 0.82 | MEN1 (0.36) | EGFRLMNAHDAC6AURKARPS6KB1 | |
| SCHEMBL30765748 | 0.81 | SOS1 (0.40) | SOS1EGFRLMNAAURKARPS6KB1 | |
| Potassium Ion SCHEMBL30765480 | 0.79 | F7 (0.36) | EGFRLMNAHDAC6 | |
| SCHEMBL30765943 | 0.78 | SOS1 (0.41) | SOS1EGFRBRD4TAF1 | |
| SCHEMBL31558541 | 0.74 | SOS1 (0.39) | SOS1EGFRLMNAAURKARPS6KB1 | |
| SCHEMBL30766075 | 0.74 | HDAC6 (0.42) | SOS1LMNAHDAC6NPY5R | |
| SCHEMBL30765619 | 0.74 | LMNA (0.38) | LMNAHDAC6NPY5R | |
| SCHEMBL31558435 | 0.73 | ELANE (0.45) | LMNAHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |