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Sugi Predict / Compounds / SCHEMBL30765487

SCHEMBL30765487

SCHEMBL30765487

CC(C)(C)OC(=O)Cn1c(-c2ccc(S(C)(=O)=NC(=O)C(F)(F)F)cc2)ncc(NCCCc2ccccc2)c1=O

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ ELANE P08246 18/20 0.41
▸ F2 P00734 1/20 0.38
▸ ALDH1A1 P00352 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ TSHR P16473 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30765692 0.91 ELANE (0.42) ELANE
SCHEMBL30765958 0.89 GAA (0.42) ELANEALDH1A1TP53TSHR
SCHEMBL30765739 0.88 F2 (0.38) ELANEF2ALDH1A1TP53TSHR
SCHEMBL30765994 0.86 ELANE (0.46) ELANEF2ALDH1A1
SCHEMBL30765457 0.84 ELANE (0.43) ELANEF2ALDH1A1
SCHEMBL30765773 0.83 ELANE (0.41) ELANEF2ALDH1A1
SCHEMBL30765873 0.82 KDM4E (0.41) ELANEF2ALDH1A1
SCHEMBL30765868 0.81 F2 (0.42) ELANEF2ALDH1A1
SCHEMBL23460649 0.81 ELANE (0.47) ELANEF2ALDH1A1
SCHEMBL30766006 0.78 KDM4E (0.42) ELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4568666-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS Alexion Pharmaceuticals, Inc. (US) 2025-06-18 — — EP disclosed
WO-2024035686-A1 PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS ALEXION PHARMACEUTICALS, INC. (US) 2024-02-15 — — WO disclosed