Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | ELANE | P08246 | 14/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ASPH | Q12797 | 1/20 | 0.34 |
| ▸ | RIOX2 | Q8IUF8 | 1/20 | 0.34 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765652 | 0.90 | KDM4E (0.38) | ELANEKDM4EASPHRIOX2KDM8 | |
| SCHEMBL30765817 | 0.88 | GAA (0.42) | ALDH1A1TP53TSHRELANEKDM4E | |
| SCHEMBL30765487 | 0.88 | ELANE (0.41) | F2ALDH1A1TP53TSHRELANE | |
| SCHEMBL30765994 | 0.86 | ELANE (0.46) | F2ALDH1A1ELANEKDM4EASPH | |
| SCHEMBL30765457 | 0.84 | ELANE (0.43) | F2ALDH1A1ELANEKDM4EASPH | |
| SCHEMBL30765773 | 0.83 | ELANE (0.41) | F2ALDH1A1ELANEKDM4EASPH | |
| SCHEMBL30765873 | 0.82 | KDM4E (0.41) | F2ALDH1A1ELANEKDM4EASPH | |
| SCHEMBL30765868 | 0.81 | F2 (0.42) | F2ALDH1A1ELANENR1H2BCL2 | |
| SCHEMBL23460649 | 0.81 | ELANE (0.47) | F2ALDH1A1ELANEKDM4EASPH | |
| SCHEMBL30765692 | 0.79 | ELANE (0.42) | ELANEKDM4EASPHRIOX2KDM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |