Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.35 |
| ▸ | KDR | P35968 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 3/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | JAK3 | P52333 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765644 | 0.88 | KDM4E (0.42) | KDM4EALDH1A1F2 | |
| SCHEMBL30766080 | 0.87 | MEN1 (0.45) | KDM4EALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL30765554 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1F2L3MBTL1 | |
| SCHEMBL23460591 | 0.86 | KDM4E (0.43) | KDM4EALDH1A1F2 | |
| SCHEMBL30765606 | 0.77 | MEN1 (0.44) | KDM4EALDH1A1TSHRMAPTL3MBTL1 | |
| SCHEMBL23474380 | 0.76 | KDM4E (0.41) | KDM4EALDH1A1F2JAK2JAK1 | |
| SCHEMBL30765933 | 0.76 | KDM4C (0.45) | KDM4EALDH1A1TSHRMAPTJAK2 | |
| SCHEMBL30765833 | 0.75 | JAK2 (0.38) | KDM4EALDH1A1F2JAK2JAK1 | |
| SCHEMBL30765873 | 0.74 | KDM4E (0.41) | KDM4EALDH1A1F2 | |
| SCHEMBL30765994 | 0.74 | ELANE (0.46) | KDM4EALDH1A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |