Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 4/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 5/20 | 0.40 |
| ▸ | CMA1 | P23946 | 4/20 | 0.40 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | SMO | Q99835 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 2/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765488 | 0.94 | NTRK1 (0.46) | HDAC1HDAC2NTRK1CMA1NTRK3 | |
| SCHEMBL31558568 | 0.92 | NTRK1 (0.45) | HDAC1HDAC2NTRK1CMA1NTRK3 | |
| SCHEMBL30765974 | 0.87 | CASP1 (0.44) | HDAC1HDAC2NTRK1CMA1NTRK3 | |
| SCHEMBL30765954 | 0.86 | HDAC1 (0.40) | HDAC1HDAC2NTRK1CMA1NTRK3 | |
| SCHEMBL30765680 | 0.84 | MAPK14 (0.49) | NTRK1NTRK3MAPK14SMO | |
| SCHEMBL30765697 | 0.83 | F2 (0.43) | HDAC6NTRK1CMA1NTRK3CASP1 | |
| SCHEMBL30765624 | 0.82 | CASP1 (0.42) | HDAC1NTRK1CMA1NTRK3CASP1 | |
| SCHEMBL31558593 | 0.82 | CMA1 (0.39) | NTRK1CMA1NTRK3CTRCF3 | |
| SCHEMBL30766005 | 0.81 | CASP1 (0.41) | HDAC1NTRK1CMA1NTRK3CASP1 | |
| SCHEMBL30765851 | 0.81 | NTRK1 (0.40) | HDAC1HDAC2HDAC3HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |