Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | NAMPT | P43490 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | F3 | P13726 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765754 | 0.90 | MAPK1 (0.34) | MAPK1NAMPTF2 | |
| SCHEMBL30765728 | 0.86 | MAPK1 (0.38) | MAPK1NAMPTF2 | |
| SCHEMBL30765646 | 0.81 | MAPK1 (0.38) | MAPK1NAMPTALDH1A1CYP2C9F2 | |
| SCHEMBL30765945 | 0.79 | F3 (0.34) | MAPK1ALDH1A1F2TP53F3 | |
| SCHEMBL30765440 | 0.79 | F7 (0.39) | MAPK1F2F3HDAC6 | |
| SCHEMBL30765753 | 0.77 | F2 (0.34) | MAPK1F2F3 | |
| SCHEMBL30765686 | 0.76 | F2 (0.35) | MAPK1NAMPTALDH1A1L3MBTL1CYP2C9 | |
| SCHEMBL30765806 | 0.76 | MAPK1 (0.36) | MAPK1NAMPTALDH1A1F2USP2 | |
| SCHEMBL30765642 | 0.75 | MAPK1 (0.35) | MAPK1NAMPTALDH1A1F2F3 | |
| SCHEMBL31558576 | 0.75 | F3 (0.35) | MAPK1ALDH1A1F2TP53F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |