Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYMP | P19971 | 5/20 | 0.44 |
| ▸ | DAO | P14920 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5365946 | 0.71 | LMNA (0.40) | DAOLMNAALDH1A1POLBMAPT | |
| SCHEMBL5378266 | 0.68 | LMNA (0.37) | DAOLMNAALDH1A1POLBMAPT | |
| SCHEMBL19051387 | 0.65 | AR (0.35) | TYMPMEN1CYP1A2CYP2C19KMT2A | |
| SCHEMBL5378526 | 0.64 | NPY5R (0.49) | ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL21388796 | 0.62 | HPGD (0.47) | ALDH1A1POLBMAPTPKMMEN1 | |
| SCHEMBL5383007 | 0.62 | NPY5R (0.50) | ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL13813416 | 0.62 | MAPT (0.41) | TYMPALDH1A1POLBMAPTKDM4C | |
| SCHEMBL31547605 | 0.61 | KDM4E (0.44) | DAOLMNAALDH1A1POLBMAPT | |
| SCHEMBL21398887 | 0.60 | KDM4E (0.44) | LMNAALDH1A1POLBMAPTKDM4C | |
| SCHEMBL4433604 | 0.60 | POLB (0.42) | LMNAALDH1A1POLBMAPTKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |