Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 9/20 | 0.37 |
| ▸ | AVPR1B | P47901 | 5/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.35 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CMA1 | P23946 | 1/20 | 0.34 |
| ▸ | CTRC | Q99895 | 1/20 | 0.34 |
| ▸ | KDM6B | O15054 | 1/20 | 0.34 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765470 | 0.97 | AVPR1B (0.37) | F2AVPR1BPRSS1CASP1CMA1 | |
| SCHEMBL30765647 | 0.92 | F2 (0.37) | F2AVPR1BPRSS1PRSS2PRSS3 | |
| SCHEMBL30765562 | 0.90 | F2 (0.36) | F2AVPR1BPRSS1PRSS2PRSS3 | |
| SCHEMBL30765912 | 0.90 | PRKAG1 (0.36) | F2AVPR1BPRSS1PRSS2PRSS3 | |
| SCHEMBL30765570 | 0.89 | AVPR1B (0.37) | F2AVPR1BPRSS1CASP1CMA1 | |
| SCHEMBL30765577 | 0.88 | AVPR1B (0.36) | F2AVPR1BPRSS1ELANECASP1 | |
| SCHEMBL30765437 | 0.87 | HDAC6 (0.41) | F2PRSS1ELANECMA1CTRC | |
| SCHEMBL30765474 | 0.86 | F2 (0.38) | F2PRSS1PRSS2PRSS3CMA1 | |
| SCHEMBL30765550 | 0.86 | F2 (0.38) | F2AVPR1BPRSS1ELANECASP1 | |
| SCHEMBL30765489 | 0.85 | F2 (0.39) | F2AVPR1BPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |