Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 5/20 | 0.40 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.37 |
| ▸ | MMP12 | P39900 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | PRKDC | P78527 | 1/20 | 0.36 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30766072 | 0.90 | SOS1 (0.39) | SOS1EGFRKDM4EALDH1A1GLA | |
| SCHEMBL30766079 | 0.87 | TSHR (0.38) | SOS1EGFRALDH1A1GAALIPG | |
| SCHEMBL30765728 | 0.82 | MAPK1 (0.38) | SOS1EGFRLIPGMAPK1 | |
| SCHEMBL30765730 | 0.81 | SOS1 (0.41) | SOS1EGFRAURKARPS6KB1LMNA | |
| SCHEMBL31558425 | 0.80 | MEN1 (0.36) | EGFRMMP12AURKARPS6KB1MEN1 | |
| SCHEMBL31558541 | 0.78 | SOS1 (0.39) | SOS1EGFRKDM4EALDH1A1SYK | |
| SCHEMBL30765863 | 0.78 | GAA (0.38) | KDM4EALDH1A1GAAMMP12LMNA | |
| SCHEMBL30765626 | 0.78 | USP2 (0.33) | ALDH1A1GAAPRKDCLMNAHTT | |
| Potassium Ion SCHEMBL30765480 | 0.78 | F7 (0.36) | EGFRMMP12LMNA | |
| SCHEMBL30766075 | 0.77 | HDAC6 (0.42) | SOS1KDM4EALDH1A1GAAMMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |