Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | PRCP | P42785 | 2/20 | 0.37 |
| ▸ | ACACB | O00763 | 1/20 | 0.37 |
| ▸ | ACACA | Q13085 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765707 | 1.00 | PTGS2 (0.40) | PTGS2MAPTALDH1A1HPGDPRCP | |
| SCHEMBL28673711 | 1.00 | PTGS2 (0.40) | PTGS2MAPTALDH1A1HPGDPRCP | |
| SCHEMBL29472427 | 1.00 | PTGS2 (0.40) | PTGS2MAPTALDH1A1HPGDPRCP | |
| SCHEMBL28673712 | 1.00 | PTGS2 (0.40) | PTGS2MAPTALDH1A1HPGDPRCP | |
| SCHEMBL24003499 | 0.90 | CHRM2 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL30238788 | 0.90 | CHRM2 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL12710431 | 0.90 | CHRM2 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL19421494 | 0.90 | CHRM2 (0.39) | ALDH1A1MEN1KMT2ACYP1A2CYP2C19 | |
| SCHEMBL22279427 | 0.84 | MAPT (0.38) | PTGS2MAPTALDH1A1HPGDPRCP | |
| SCHEMBL22158879 | 0.83 | ACACB (0.47) | ALDH1A1HPGDACACBACACAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |