Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 4/20 | 0.33 |
| ▸ | CTRC | Q99895 | 2/20 | 0.33 |
| ▸ | CMA1 | P23946 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765704 | 0.84 | KDM4E (0.43) | POLBKDM4EALDH1A1TP53 | |
| SCHEMBL5565965 | 0.83 | POLB (0.38) | POLBADORA2BKDM4EALDH1A1HPGD | |
| SCHEMBL6800734 | 0.80 | GAA (0.40) | ADORA2BKDM4EALDH1A1HPGDGAA | |
| SCHEMBL6804071 | 0.72 | ELANE (0.50) | POLBALDH1A1HPGDELANECTRC | |
| SCHEMBL6239360 | 0.72 | CMA1 (0.53) | KDM4EELANECTRCCMA1 | |
| SCHEMBL6804111 | 0.71 | CMA1 (0.53) | KDM4EELANECTRCCMA1 | |
| Hydrochloric Acid SCHEMBL6805327 | 0.71 | CMA1 (0.53) | KDM4EELANECTRCCMA1 | |
| SCHEMBL6801619 | 0.71 | TSHR (0.45) | KDM4EALDH1A1HPGDELANECTRC | |
| SCHEMBL6802585 | 0.70 | ELANE (0.40) | ELANECTRCCMA1 | |
| SCHEMBL6805368 | 0.69 | ELANE (0.53) | ELANECTRCCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| CN-119768164-A | Pharmaceutical compounds for treating complement-mediated disorders | 阿雷克森制药公司 | 2025-04-04 | — | — | CN | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |