Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | JAK1 | P23458 | 1/20 | 0.36 |
| ▸ | TYK2 | P29597 | 1/20 | 0.36 |
| ▸ | JAK3 | P52333 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CDK4 | P11802 | 1/20 | 0.36 |
| ▸ | CCND1 | P24385 | 1/20 | 0.36 |
| ▸ | CCND2 | P30279 | 1/20 | 0.36 |
| ▸ | CCND3 | P30281 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30765971 | 0.84 | POLB (0.38) | KDM4EALDH1A1TP53POLB | |
| SCHEMBL30765599 | 0.75 | CTRC (0.54) | KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL23461141 | 0.70 | KDM4E (0.46) | KDM4ESMN1; SMN2ALDH1A1NPC1JAK2 | |
| SCHEMBL27459972 | 0.69 | KDM4E (0.53) | KDM4ESMN1; SMN2ALDH1A1HSD17B10NPC1 | |
| SCHEMBL30765906 | 0.69 | SMN1; SMN2 (0.45) | KDM4ESMN1; SMN2ALDH1A1HSD17B10NPC1 | |
| SCHEMBL23460858 | 0.69 | KDM4E (0.48) | KDM4ESMN1; SMN2ALDH1A1HSD17B10 | |
| SCHEMBL23474380 | 0.68 | KDM4E (0.41) | KDM4EALDH1A1JAK2JAK1JAK3 | |
| SCHEMBL5565965 | 0.68 | POLB (0.38) | KDM4ESMN1; SMN2ALDH1A1HSD17B10NPC1 | |
| SCHEMBL11046960 | 0.68 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1TP53MAPTPOLB | |
| SCHEMBL30765661 | 0.68 | MEN1 (0.48) | KDM4ESMN1; SMN2ALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568666-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | Alexion Pharmaceuticals, Inc. (US) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024035686-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT MEDIATED DISORDERS | ALEXION PHARMACEUTICALS, INC. (US) | 2024-02-15 | — | — | WO | disclosed |