Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | DPP4 | P27487 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12677914 | 0.74 | HCAR2 (0.50) | ALDH1A1CYP11B2L3MBTL1MEN1KMT2A | |
| SCHEMBL25624678 | 0.71 | ATM (0.51) | ALDH1A1CYP11B2MAP4K4OPRK1KCNH2 | |
| SCHEMBL3931389 | 0.71 | NPC1 (0.47) | ALDH1A1LMNAMAP4K4L3MBTL1MEN1 | |
| SCHEMBL12168345 | 0.69 | CYP11B1 (0.44) | ALDH1A1LMNACYP11B2MAP4K4MEN1 | |
| SCHEMBL17572997 | 0.69 | DYRK1A (0.48) | KCNH2 | |
| Hydrochloric Acid SCHEMBL17559422 | 0.68 | DYRK1A (0.48) | KCNH2 | |
| SCHEMBL23021934 | 0.67 | POLB (0.40) | ALDH1A1L3MBTL1MEN1KMT2APOLB | |
| SCHEMBL31359370 | 0.67 | ATM (0.46) | CYP11B2OPRK1KCNH2 | |
| SCHEMBL23501627 | 0.67 | ATM (0.46) | CYP11B2OPRK1KCNH2 | |
| SCHEMBL15996726 | 0.67 | CHRNB2 (0.45) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4565569-A1 | ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2025-06-11 | — | — | EP | disclosed |
| WO-2024028364-A1 | ARYL-TRIAZOLYL AND RELATED GPR84 ANTAGONISTS AND USES THEREOF | Liminal Biosciences Limited (GB) | 2024-02-08 | — | — | WO | disclosed |