SCHEMBL30766458

SCHEMBL30766458

O=Cc1cc(Cl)cc(-c2ccccc2F)c1[N+](=O)[O-]

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.38
TSHR P16473 2/20 0.38
ERN1 O75460 3/20 0.36
MAPT P10636 4/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
EPAS1 Q99814 2/20 0.34
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
ARNT P27540 1/20 0.33
MEN1 O00255 3/20 0.33
KMT2A Q03164 3/20 0.33
LMNA P02545 2/20 0.32
MAPK1 P28482 1/20 0.32
NTSR1 P30989 1/20 0.32
HCRTR1 O43613 1/20 0.32
PKM P14618 1/20 0.32
HTT P42858 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
CYP3A4 P08684 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29005655 0.77 TSHR (0.56) ALDH1A1TSHRERN1MAPTMEN1
SCHEMBL2448929 0.74 TDP1 (0.48) ERN1LMNASMN1; SMN2
SCHEMBL2991343 0.72 ALDH1A1 (0.43) ALDH1A1TSHRERN1MAPTNPC1
SCHEMBL30766284 0.72 TSHR (0.67) ALDH1A1TSHRERN1MAPTMEN1
SCHEMBL203116 0.72 TSHR (0.67) ALDH1A1TSHRERN1MAPTMEN1
SCHEMBL27735806 0.72 MAPK1 (0.51) ALDH1A1TSHRMAPTMEN1KMT2A
SCHEMBL25680078 0.71 NPC1 (0.39) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL27756639 0.71 NPC1 (0.40) ALDH1A1TSHRMAPTNPC1RAB9A
SCHEMBL10462442 0.71 TSHR (0.48) ALDH1A1TSHRERN1MAPTNPC1
SCHEMBL27735809 0.70 NPC1 (0.43) ALDH1A1TSHRMAPTNPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024026536-A1 ANTIVIRAL COMPOUNDS AND USES THEREOF GRIFFITH UNIVERSITY (AU) 2024-02-08 WO disclosed