Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 14/20 | 0.80 |
| ▸ | DRD2 | P14416 | 14/20 | 0.80 |
| ▸ | HTR2A | P28223 | 14/20 | 0.80 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.80 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.80 |
| ▸ | HPGD | P15428 | 2/20 | 0.80 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.80 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.80 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.80 |
| ▸ | HRH1 | P35367 | 2/20 | 0.80 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.80 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.80 |
| ▸ | LMNA | P02545 | 1/20 | 0.80 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.80 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.80 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.80 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.80 |
| ▸ | DRD1 | P21728 | 1/20 | 0.80 |
| ▸ | DRD4 | P21917 | 1/20 | 0.80 |
| ▸ | HRH2 | P25021 | 1/20 | 0.80 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL30945326 | 0.99 | KDM4E (0.81) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| SCHEMBL30767220 | 0.91 | HTR1A (0.80) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL28167 | 0.89 | HTR1A (1.00) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL29390760 | 0.89 | HTR1A (1.00) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL28226073 | 0.88 | HTR1A (0.98) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL3402550 | 0.88 | KDM4E (1.00) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL61754 | 0.88 | KDM4E (1.00) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL29575935 | 0.88 | KDM4E (1.00) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| SCHEMBL11174569 | 0.88 | HTR1A (0.78) | HTR1ADRD2HTR2AKDM4EALDH1A1 | |
| Trazodone SCHEMBL120883 | 0.87 | HTR1A (0.96) | HTR1ADRD2HTR2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117470987-A | Detection method of trazodone hydrochloride related substances | 湖南省湘中制药有限公司 | 2024-01-30 | — | — | CN | disclosed |