Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 12/20 | 0.51 |
| ▸ | IP6K1 | Q92551 | 2/20 | 0.42 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.39 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.39 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.37 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | WIZ | O95785 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | TDO2 | P48775 | 1/20 | 0.37 |
| ▸ | IDO2 | Q6ZQW0 | 1/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767222 | 0.92 | CRBN (0.57) | CRBNIP6K1DDB1IKZF3PDE3B | |
| SCHEMBL27012609 | 0.91 | CRBN (0.49) | CRBNDDB1IKZF3IDO1TDO2 | |
| SCHEMBL22326226 | 0.87 | CRBN (0.47) | CRBNIP6K1DDB1IKZF3PDE3B | |
| SCHEMBL22326268 | 0.84 | CRBN (0.47) | CRBNDDB1IKZF3ALDH1A1CYP1A2 | |
| SCHEMBL21751118 | 0.82 | CRBN (0.55) | CRBNDDB1IKZF3ALDH1A1CYP1A2 | |
| SCHEMBL24233170 | 0.81 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CYP1A2 | |
| SCHEMBL21751104 | 0.81 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CYP1A2 | |
| SCHEMBL23534466 | 0.81 | CRBN (0.57) | CRBNDDB1IKZF3ALDH1A1CYP1A2 | |
| SCHEMBL21751067 | 0.81 | CRBN (0.54) | CRBNDDB1IKZF3ALDH1A1CYP1A2 | |
| SCHEMBL21751098 | 0.81 | CRBN (0.56) | CRBNDDB1IKZF3ALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240018123-A1 | COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2024-01-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240018123-A1 | COMPOUND FOR INHIBITING OR DISINTEGRATING ANDROGEN RECEPTOR, AND PHARMACEUTICAL USE THEREOF | AR, NR5A1, SHBG | CRBN 3597/4885IP6K1 3501/4885IP6K3 2908/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.