Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 3/20 | 0.33 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.31 |
| ▸ | XIAP | P98170 | 2/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767505 | 1.00 | NPY1R (0.33) | NPY1RBTKSCN9AXIAPRIPK1 | |
| SCHEMBL31665008 | 0.92 | GRM2 (0.33) | NPY1R | |
| SCHEMBL30767525 | 0.92 | SCN9A (0.34) | NPY1RBTKSCN9A | |
| SCHEMBL30767420 | 0.92 | CNR1 (0.32) | XIAP | |
| SCHEMBL30767615 | 0.92 | CNR1 (0.32) | XIAP | |
| SCHEMBL30767411 | 0.92 | CNR1 (0.32) | XIAP | |
| SCHEMBL30767542 | 0.91 | NPY1R (0.33) | NPY1RBTKSCN9AXIAP | |
| SCHEMBL30767680 | 0.91 | NPY1R (0.33) | NPY1RBTKSCN9AXIAP | |
| SCHEMBL30767612 | 0.91 | NPY1R (0.33) | NPY1RBTKSCN9AXIAP | |
| SCHEMBL30767318 | 0.88 | CHRM5 (0.33) | BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |