Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.32 |
| ▸ | XIAP | P98170 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.31 |
| ▸ | MCHR1 | Q99705 | 5/20 | 0.31 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.30 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.30 |
| ▸ | F10 | P00742 | 1/20 | 0.30 |
| ▸ | CTSL | P07711 | 1/20 | 0.30 |
| ▸ | CTSB | P07858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30767411 | 1.00 | CNR1 (0.32) | CNR1CNR2FAAHABHD6XIAP | |
| SCHEMBL30767420 | 1.00 | CNR1 (0.32) | CNR1CNR2FAAHABHD6XIAP | |
| SCHEMBL30767587 | 0.93 | CPB2 (0.32) | PDE2A | |
| SCHEMBL30767594 | 0.93 | CPB2 (0.32) | PDE2A | |
| SCHEMBL30767479 | 0.93 | CPB2 (0.32) | PDE2A | |
| SCHEMBL31665008 | 0.93 | GRM2 (0.33) | FAAH | |
| SCHEMBL30767412 | 0.92 | NPY1R (0.33) | XIAP | |
| SCHEMBL30767505 | 0.92 | NPY1R (0.33) | XIAP | |
| SCHEMBL30767620 | 0.91 | F10 (0.32) | CNR1CNR2FAAHABHD6XIAP | |
| SCHEMBL30767676 | 0.91 | F10 (0.32) | CNR1CNR2FAAHABHD6XIAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |