Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCG | P01275 | 7/20 | 0.47 |
| ▸ | GCGR | P47871 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22534381 | 0.84 | RAB9A (0.49) | RAB9ALMNANPC1KMT2AMAPK1 | |
| SCHEMBL11962743 | 0.82 | GCG (0.60) | GCGGCGR | |
| SCHEMBL11900131 | 0.80 | GCG (0.52) | GCGGCGREGLN1 | |
| SCHEMBL11899556 | 0.79 | GCGR (0.75) | GCGGCGR | |
| SCHEMBL11899687 | 0.79 | GCG (0.51) | GCGGCGRMAPTEGLN1SMN1; SMN2 | |
| SCHEMBL15350675 | 0.77 | GCG (0.46) | GCGGCGRLMNAMAPK1KDM4E | |
| SCHEMBL30767560 | 0.77 | CYP1A2 (0.60) | GCGGCGRLMNAKDM4EL3MBTL1 | |
| SCHEMBL30767554 | 0.77 | CFTR (0.43) | GCGGCGRRAB9ALMNANPC1 | |
| SCHEMBL31706156 | 0.76 | SLC34A1 (0.42) | GCGGCGRLMNAMAPK1MAPT | |
| SCHEMBL31705370 | 0.76 | SLC34A1 (0.42) | GCGGCGRLMNAMAPK1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4568960-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. Hoffmann-La Roche AG (CH) | 2025-06-18 | — | — | EP | disclosed |
| WO-2024033458-A1 | BICYCLIC TETRAHYDROAZEPINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2024-02-15 | — | — | WO | disclosed |