SCHEMBL30767995

SCHEMBL30767995

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nearest known ligand 0.61

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.61
TSHR P16473 2/20 0.61
LMNA P02545 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
TXNRD1 Q16881 6/20 0.51
TXNRD3 Q86VQ6 6/20 0.51
TXNRD2 Q9NNW7 6/20 0.51
HDAC3 O15379 1/20 0.41
HDAC1 Q13547 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
FYN P06241 1/20 0.37
MAOA P21397 1/20 0.37
SLC6A2 P23975 1/20 0.37
HTR2C P28335 1/20 0.37
HTR2B P41595 1/20 0.37
SLC6A3 Q01959 1/20 0.37
LGALS3 P17931 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9099489 0.89 ALDH1A1 (0.48) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL8265 0.85 ALDH1A1 (0.50) ALDH1A1TSHRLMNATDP1TXNRD1
Alfadex SCHEMBL25414284 0.84 ALDH1A1 (0.80) ALDH1A1TSHRLMNATDP1TXNRD1
Alfadex SCHEMBL25413932 0.84 ALDH1A1 (0.80) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL1056613 0.80 ALDH1A1 (0.62) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL2305805 0.80 ALDH1A1 (0.62) ALDH1A1TSHRLMNATDP1TXNRD1
Gamma-Cyclodextrin SCHEMBL16384436 0.80 ALDH1A1 (0.95) ALDH1A1TSHRLMNATDP1TXNRD1
SCHEMBL29899136 0.79 ALDH1A1 (0.71) ALDH1A1TSHRLMNATDP1TXNRD1
Gamma-Cyclodextrin SCHEMBL25455463 0.78 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1
Alfadex SCHEMBL25455476 0.78 ALDH1A1 (1.00) ALDH1A1TSHRLMNATDP1TXNRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110191949-B Recombinant virus, composition comprising same and use thereof 周美吟 2024-02-20 CN disclosed