Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 20/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.52 |
| ▸ | CDK1 | P06493 | 5/20 | 0.52 |
| ▸ | CCNB1 | P14635 | 5/20 | 0.52 |
| ▸ | CCNB2 | O95067 | 3/20 | 0.52 |
| ▸ | CCNE2 | O96020 | 3/20 | 0.52 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.52 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.52 |
| ▸ | CCNB3 | Q8WWL7 | 3/20 | 0.52 |
| ▸ | CCND1 | P24385 | 5/20 | 0.51 |
| ▸ | CDK6 | Q00534 | 5/20 | 0.51 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.51 |
| ▸ | CDK4 | P11802 | 2/20 | 0.51 |
| ▸ | CCND3 | P30281 | 2/20 | 0.51 |
| ▸ | CDK9 | P50750 | 2/20 | 0.51 |
| ▸ | CDK7 | P50613 | 1/20 | 0.51 |
| ▸ | CCNH | P51946 | 1/20 | 0.51 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.51 |
| ▸ | CCNA2 | P20248 | 6/20 | 0.44 |
| ▸ | CCNK | O75909 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035003 | 1.00 | CDK2 (0.52) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL30726194 | 0.84 | CCNE1 (0.57) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL27033634 | 0.84 | CCNE1 (0.57) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL27034820 | 0.83 | CCNE1 (0.49) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL30768109 | 0.83 | CCNE1 (0.49) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL30761953 | 0.80 | CDK2 (0.50) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL27035016 | 0.80 | CDK2 (0.50) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL22977319 | 0.80 | CDK2 (0.67) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL29631714 | 0.80 | CDK2 (0.53) | CDK2CCNE1CDK1CCNB1CCNB2 | |
| SCHEMBL24477981 | 0.80 | CDK2 (0.53) | CDK2CCNE1CDK1CCNB1CCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |