Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE1 | P24864 | 20/20 | 0.49 |
| ▸ | CDK2 | P24941 | 20/20 | 0.49 |
| ▸ | CCND1 | P24385 | 14/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 14/20 | 0.49 |
| ▸ | CDK1 | P06493 | 4/20 | 0.46 |
| ▸ | CCNB1 | P14635 | 4/20 | 0.46 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.46 |
| ▸ | CDK4 | P11802 | 3/20 | 0.46 |
| ▸ | CDK9 | P50750 | 3/20 | 0.46 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.46 |
| ▸ | CCNE2 | O96020 | 2/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.46 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.46 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.46 |
| ▸ | CCND3 | P30281 | 2/20 | 0.46 |
| ▸ | CDK7 | P50613 | 1/20 | 0.42 |
| ▸ | CCNH | P51946 | 1/20 | 0.42 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27034820 | 1.00 | CCNE1 (0.49) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30726194 | 0.90 | CCNE1 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL27033634 | 0.90 | CCNE1 (0.57) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30768108 | 0.83 | CCNE1 (0.51) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL27034836 | 0.83 | CCNE1 (0.51) | CCNE1CDK2CCND1CDK6CCNT1 | |
| SCHEMBL27035003 | 0.83 | CDK2 (0.52) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30768097 | 0.83 | CDK2 (0.52) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30768098 | 0.80 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL27034859 | 0.80 | CCNE1 (0.56) | CCNE1CDK2CCND1CDK6CDK1 | |
| SCHEMBL30761970 | 0.79 | CCNE1 (0.44) | CCNE1CDK2CCND1CDK6CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-120051470-A | Azaquinazoline compounds and methods of use | 依安彼克医疗有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |