Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 17/20 | 0.42 |
| ▸ | CCNE1 | P24864 | 14/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 3/20 | 0.40 |
| ▸ | CCND1 | P24385 | 10/20 | 0.39 |
| ▸ | CDK4 | P11802 | 4/20 | 0.39 |
| ▸ | CDK1 | P06493 | 3/20 | 0.39 |
| ▸ | CDK6 | Q00534 | 7/20 | 0.38 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27035006 | 1.00 | CDK2 (0.42) | CDK2CCNE1GPR119CCND1CDK4 | |
| SCHEMBL27035011 | 0.81 | CCNE1 (0.41) | CDK2CCNE1CCND1CDK4CDK6 | |
| SCHEMBL30761934 | 0.81 | CCNE1 (0.41) | CDK2CCNE1CCND1CDK4CDK6 | |
| SCHEMBL27034821 | 0.79 | GPR119 (0.42) | CDK2CCNE1GPR119CCND1CDK4 | |
| SCHEMBL30768103 | 0.79 | GPR119 (0.42) | CDK2CCNE1GPR119CCND1CDK4 | |
| SCHEMBL27060629 | 0.79 | CCNE1 (0.46) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30761989 | 0.79 | CCNE1 (0.46) | CDK2CCNE1CCND1CDK4CDK1 | |
| SCHEMBL30726210 | 0.72 | GPR119 (0.43) | CDK2CCNE1GPR119CCND1CDK4 | |
| SCHEMBL27033325 | 0.72 | GPR119 (0.43) | CDK2CCNE1GPR119CCND1CDK4 | |
| SCHEMBL30726192 | 0.72 | CDK2 (0.42) | CDK2CCNE1GPR119CCND1CDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4558502-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | Iambic Therapeutics, Inc. (US) | 2025-05-28 | — | — | EP | disclosed |
| CN-120051470-A | Azaquinazoline compounds and methods of use | 依安彼克医疗有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024020419-A1 | AZA-QUINAZOLINE COMPOUNDS AND METHODS OF USE | IAMBIC THERAPEUTICS, INC. (US) | 2024-01-25 | — | — | WO | disclosed |