Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29201123 | 1.00 | MEN1 (0.67) | MEN1KMT2ASIRT6MAPTKDM4E | |
| SCHEMBL6609282 | 0.80 | MEN1 (1.00) | MEN1KMT2ASIRT6MAPTKDM4E | |
| SCHEMBL28457709 | 0.80 | EED (0.46) | MEN1KMT2AMAPTALDH1A1LMNA | |
| SCHEMBL28940436 | 0.79 | ACACB (0.56) | MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL29644378 | 0.79 | ACACB (0.56) | MAPTKDM4EALDH1A1LMNA | |
| SCHEMBL28739023 | 0.78 | HPGD (0.70) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL29644426 | 0.78 | HPGD (0.70) | MEN1KMT2AMAPTALDH1A1POLB | |
| SCHEMBL30874289 | 0.76 | HTR3E (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL29229997 | 0.76 | HTR3E (0.42) | MEN1KMT2AMAPTKDM4EALDH1A1 | |
| SCHEMBL7995398 | 0.72 | KMT2A (0.65) | MEN1KMT2ASIRT6MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114507181-B | Propionic acid compound containing 5-substituted tetrahydroisoquinoline, pharmaceutical composition and application thereof | 中国医学科学院药物研究所 | 2024-03-26 | — | — | CN | disclosed |