Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | CFB | P00751 | 5/20 | 0.48 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21625238 | 1.00 | MEN1 (0.50) | MEN1KMT2ACFBCHRM4CYP3A4 | |
| SCHEMBL28540053 | 0.81 | SIGMAR1 (0.47) | KDM1A | |
| SCHEMBL30052834 | 0.81 | SIGMAR1 (0.47) | KDM1A | |
| SCHEMBL28529378 | 0.81 | SIGMAR1 (0.47) | KDM1A | |
| SCHEMBL29148961 | 0.81 | SIGMAR1 (0.47) | KDM1A | |
| SCHEMBL24179625 | 0.81 | SIGMAR1 (0.47) | KDM1A | |
| SCHEMBL30053112 | 0.81 | SIGMAR1 (0.47) | KDM1A | |
| SCHEMBL3890628 | 0.80 | CFB (0.47) | CFBALDH1A1MAPT | |
| SCHEMBL6497571 | 0.80 | CFB (0.47) | MEN1KMT2ACFBALDH1A1MAPT | |
| SCHEMBL3901486 | 0.80 | NPC1 (0.45) | CFBOPRM1OPRK1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117500499-A | Substituted indole compounds and methods of use thereof | 奇努克治疗公司 | 2024-02-02 | — | — | CN | disclosed |