Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 19/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 18/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30768911 | 0.79 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30769408 | 0.79 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30768538 | 0.78 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30768686 | 0.78 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30768750 | 0.78 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30769247 | 0.78 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30769044 | 0.77 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30768954 | 0.77 | ESR1 (0.43) | ESR1ESR2 | |
| SCHEMBL30769175 | 0.76 | ESR1 (0.47) | ESR1ESR2CA1CA2CA7 | |
| SCHEMBL30769315 | 0.75 | ESR1 (0.47) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543871-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | Relay Therapeutics, Inc. (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024006781-A1 | ESTROGEN RECEPTOR ALPHA DEGRADERS AND USE THEREOF | RELAY THERAPEUTICS, INC. (US) | 2024-01-04 | — | — | WO | disclosed |