⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28115278 | 0.73 | POLB (0.50) | — | |
| SCHEMBL3090858 | 0.73 | — | — | |
| SCHEMBL629080 | 0.71 | — | — | |
| SCHEMBL27731937 | 0.71 | — | — | |
| SCHEMBL674966 | 0.71 | — | — | |
| SCHEMBL455088 | 0.71 | — | — | |
| SCHEMBL2126503 | 0.71 | — | — | |
| SCHEMBL19784971 | 0.71 | — | — | |
| SCHEMBL2002173 | 0.71 | — | — | |
| SCHEMBL8133286 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115397804-A | Dextromethorphan for disease modifying treatment of neuropsychiatric disorders and diseases | 帕多瓦大学 | 2022-11-25 | — | — | CN | claimed |
| EP-1590314-B1 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPÉ FARMACEUTICI S P A (IT) | 2015-08-05 | — | — | EP | claimed |
| EP-1590314-A2 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dompe' S.P.A. (IT) | 2005-11-02 | — | — | EP | claimed |
| WO-2004069782-A2 | 2-ARYL-ACETIC ACIDS, THEIR DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DOMPE' S.P.A. (IT) | 2004-08-19 | — | — | WO | claimed |
| EP-0193066-B1 | KETOSULTAMS AND PROCESS FOR THEIR PREPARATION | HOECHST AKTIENGESELLSCHAFT (DE) | 1989-01-04 | — | — | EP | claimed |
| US-4691056-A | 3-halogenoacetonesulfonamides and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | claimed |
| EP-0193066-A1 | Ketosultams and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-09-03 | — | — | EP | claimed |
| CN-112424201-B | Protein kinase inhibitors that promote liver regeneration or reduce or prevent hepatocyte death | 海帕瑞吉尼克斯股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| US-20230139597-A1 | HORMONE RECEPTOR MODULATORS FOR TREATING METABOLIC CONDITIONS AND DISORDERS | ARDELYX, INC. (US) | 2023-05-04 | — | — | US | disclosed |
| CN-115667263-A | Pyrrolo [2,3-D ] pyrimidine derivatives | 辉瑞公司 | 2023-01-31 | — | — | CN | disclosed |
| CN-115397804-A | Dextromethorphan for disease modifying treatment of neuropsychiatric disorders and diseases | 帕多瓦大学 | 2022-11-25 | — | — | CN | disclosed |
| EP-4023636-A1 | ACTINIC RAY-SENSITIVE OR RADIATION-SENSITIVE RESIN COMPOSITION, PATTERN FORMATION METHOD, RESIST FILM, AND ELECTRONIC DEVICE PRODUCTION METHOD | FUJIFILM Corporation (JP) | 2022-07-06 | — | — | EP | disclosed |
| EP-2970278-A1 | PYRROLO[2,3-B]PYRIDINE CDK9 KINASE INHIBITORS | AbbVie Inc. (US) | 2016-01-20 | — | — | EP | disclosed |
| US-4709026-A | INTERMEDIATES FOR SULFONE-CONTAINING STYRENE DERIVATIVE SENSITIZERS AND DYES | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-11-24 | — | — | US | disclosed |
| US-4691056-A | 3-halogenoacetonesulfonamides and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | disclosed |
| US-4691056-A | 3-halogenoacetonesulfonamides and a process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-09-01 | — | — | US | disclosed |
| EP-0134934-B1 | 2-KETO-SULPHON AMIDES AND PROCESS FOR THEIR PRODUCTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-03-04 | — | — | EP | disclosed |
| US-4628109-A | 2-ketosulfonamides and process for their preparation | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-12-09 | — | — | US | disclosed |
| EP-0134934-A1 | 2-Keto-sulphon amides and process for their production | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-03-27 | — | — | EP | disclosed |
| US-4448988-A | 2-Ketosulfonamides | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-05-15 | — | — | US | disclosed |